Chronically Deafferented Sensory Cortex Recovers a Grossly Typical Organization after Allogenic Hand Transplantation
نویسندگان
چکیده
منابع مشابه
Chronically Deafferented Sensory Cortex Recovers a Grossly Typical Organization after Allogenic Hand Transplantation
Amputation induces substantial reorganization of the body part somatotopy in primary sensory cortex (S1 complex, hereafter S1) [1, 2], and these effects of deafferentiation increase with time [3]. Determining whether these changes are reversible is critical for understanding the potential to recover from deafferenting injuries. Earlier BOLD fMRI data demonstrate increased S1 activity in respons...
متن کاملALLOGENIC BONE MARROW TRANSPLANTATION IN APLASTIC ANEMIA
Eighteen patients, twelve men and six women, with aplastic anemia underwent allogenic bone marrow transplantation (BMT) from HLA-matched siblings during the period of 1990 to 1996. The conditioning regimen was cyclophosphamide with or without busulfan, depending on the cause of aplasia. Antilymphocyte globulin (ALG) and cyclosporine were used for rejection and acute GVHD prophylaxis, respe...
متن کامل[Allogenic bone marrow transplantation].
Allogeneic bone marrow transplantation (BMT) after high-dose, marrow-ablative chemoradiotherapy has been established as the treatment of choice for various hematologic, neoplastic, and congenital disorders. The most common type of marrow graft is an allogeneic one from a sibling donor who has compatible human leukocyte antigen (HLA). Only 30% of patients requiring allogeneic BMT have an HLA-com...
متن کاملOrganization and Reorganization of Sensory-Deprived Cortex
The scientific literature has grown rich in research illustrating the remarkable ability of the brain to reorganize itself following sensory loss. In particular, visually deafferented regions within the occipital cortex of early blind individuals have been repeatedly shown to be functionally recruited to carry out a wide variety of nonvisual tasks. While the novelty of such a finding might be w...
متن کاملLung function changes after allogenic bone marrow transplantation.
The lung function of 21 patients with leukaemia (11 with acute myeloid leukaemia, six with acute lymphatic leukaemia, four with chronic myeloid leukaemia) and of five with severe aplastic anaemia was tested before and after allogenic bone marrow transplantation. Vital capacity (VC) was lowered in patients with leukaemia before transplantation. VC and FEV1 fell significantly after transplantatio...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Current Biology
سال: 2008
ISSN: 0960-9822
DOI: 10.1016/j.cub.2008.08.051